In vitro heating with polyethylene glycol coated Fe nanoparticles

被引:7
作者
Bonder, M. J. [1 ]
Srinivasan, B.
Poirier, G.
Moriyama, T.
Kiick, K. L.
Hadjipanayis, G. C.
机构
[1] Univ Delaware, Dept Phys, Newark, DE 19716 USA
[2] Univ Delaware, Dept Mat Sci & Engn, Newark, DE 19716 USA
基金
美国国家科学基金会;
关键词
biomedical applications; induction heating; magnetic nanoparticles; polyethylene glycol;
D O I
10.1109/TMAG.2006.879075
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Magnetic nanoparticles coated with a biocompatible polymer are potential candidates for biomedical applications associated with the detection and treatment of cancer. By varying the length of a reaction tube, the nanoparticle size increases from 10 to 30 nm with a 1-3 nm carboxyl terminated polyethylene glycol (cPEG) coating. The saturation magnetization for all samples is greater than 100 emu/g. By increasing the length of the reaction tube there is an incorporation of an amorphous phase. Subjecting samples to a 4 Oe magnetic field oscillating at 500 kHz there are two characteristic temperatures depending on particle size. The temperature measured for larger particles saturates with time to 35 degrees C. Below a critical nanoparticle size the temperature reached exceeds 50 degrees C within the same timeframe.
引用
收藏
页码:3602 / 3604
页数:3
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