Bacteriophages and biotechnology: vaccines, gene therapy and antibacterials

被引：224

作者：

Clark, JR ^{[1
]}

March, JB ^{[1
]}

机构：

[1] Moredun Res Inst, Penicuik EH26 0PZ, Midlothian, Scotland

来源：

TRENDS IN BIOTECHNOLOGY | 2006年 / 24卷 / 05期

关键词：

D O I：

10.1016/j.tibtech.2006.03.003

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

In recent years it has been recognized that bacteriophages have several potential applications in the modern biotechnology industry: they have been proposed as delivery vehicles for protein and DNA vaccines; as gene therapy delivery vehicles; as alternatives to antibiotics; for the detection of pathogenic bacteria; and as tools for screening libraries of proteins, peptides or antibodies. This diversity, and the ease of their manipulation and production, means that they have potential uses in research, therapeutics and manufacturing in both the biotechnology and medical fields. It is hoped that the wide range of scientists, clinicians and biotechnologists currently researching or putting phages to practical use are able to pool their knowledge and expertise and thereby accelerate progress towards further development in this exciting field of biotechnology.

引用

页码：212 / 218

页数：7

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