An expeditious route towards pyranopyran sugar amino acids

被引：19

作者：

Grotenbreg, GM ^{[1
]}

Tuin, AW ^{[1
]}

Witte, MD ^{[1
]}

Leeuwenburgh, MA ^{[1
]}

van Boom, JH ^{[1
]}

van der Marel, GA ^{[1
]}

Overkleeft, HS ^{[1
]}

Overhand, M ^{[1
]}

机构：

[1] Leiden Univ, Leiden Inst Chem, Gorlaeus Labs, NL-2300 RA Leiden, Netherlands

来源：

SYNLETT | 2004年 / 05期

关键词：

amino acids; bicyclic compounds; carbohydrates; pyranopyran; ring-closing metathesis;

D O I：

10.1055/s-2004-820021

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of two diastereoisomeric pyranopyran sugar amino acids, starting from (+)-D-3,4,6-tri-O-benzylglucal, is described. The key reaction sequence towards the bicyclic structure entails Petasis olefination followed by ring closing metathesis.

引用

页码：904 / 906

页数：3

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