DNA-magnetite nanocomposite materials

被引：60

作者：

Mornet, S

Vekris, A

Bonnet, J

Duguet, E

Grasset, F

Choy, JH

Portier, J

机构：

[1] CNRS, ICMCB, F-33608 Pessac, France

[2] Grp Interet Sci VIVO, F-33608 Pessac, France

[3] Univ Bordeaux 2, Grp Pharmacol Medicaments Anticanc, F-33076 Bordeaux, France

[4] Seoul Natl Univ, Dept Chem, Ctr Mol Catalysis, Seoul 151742, South Korea

来源：

MATERIALS LETTERS | 2000年 / 42卷 / 03期

关键词：

DNA; magnetite; nanoparticles; hybrids; biohybrids;

D O I：

10.1016/S0167-577X(99)00181-0

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

It is shown here that magnetite nanoparticles can be associated with double-stranded DNA. In a first step, a complex of DNA with Fe2+ and Fe3+ ions is formed. + Then, in a second step, magnetite nanoparticles are formed by increasing the pH. As shown by electrophoresis, the nanoparticles are strongly attached to the nucleic acid. From TEM imaging and Mossbauer measurement, a tentative model for the textural organization of DNA and magnetite is proposed. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：183 / 188

页数：6

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