Alu sequences

被引：148

作者：

Mighell, AJ ^{[1
]}

Markham, AF ^{[1
]}

Robinson, PA ^{[1
]}

机构：

[1] LEEDS DENT INST, LEEDS LS2 9LU, W YORKSHIRE, ENGLAND

来源：

FEBS LETTERS | 1997年 / 417卷 / 01期

基金：

英国惠康基金;

关键词：

Alu; repetitive DNA; retrotransposon; polymerase II; polymerase III; human genome;

D O I：

10.1016/S0014-5793(97)01259-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Alu sequences are frequently encountered during study of human genomic nucleic acid and form a major component of repetitive DNA. This review describes the origin of Alu sequences and their subsequent amplification and evolution into distinct subfamilies, In recent years a number of different functional roles for Alu sequences have been described, The multiple influences of Alu sequences on RNA polymerase II-mediated gene expression and the presence of Alu sequences in RNA polymerase III-generated transcripts are discussed. (C) 1997 Federation of European Biochemical Societies.

引用

页码：1 / 5

页数：5

共 79 条

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