Methods for a population-based study of the prevalence of and risk factors for age-related maculopathy and macular degeneration in elderly European populations: the EUREYE study

被引:61
作者
Augood, C
Fletcher, A
Bentham, G
Chakravarthy, U
de Jong, PVTM
Rahu, M
Seland, J
Soubrane, G
Tomazzoli, L
Topouzis, F
Vioque, J
Young, I
机构
[1] Univ London London Sch Hyg & Trop Med, Dept Epidemiol & Populat Hlth, Noncommunicable Dis Epidemiol Unit, London WC1E 7HT, England
[2] Univ E Anglia, Sch Environm Sci, Ctr Environm Risk, Norwich NR4 7TJ, Norfolk, England
[3] Royal Victoria Hosp, Dept Ophthalmol, Belfast BT12 6BA, Antrim, North Ireland
[4] Queens Univ Belfast, Inst Clin Sci, Dept Clin Biochem, Belfast BT12 6BJ, Antrim, North Ireland
[5] NORI, Amsterdam, Netherlands
[6] Inst Clin & Expt Med, Tallinn, Estonia
[7] Haukeland Hosp, Oyeavdelingen, N-5021 Bergen, Norway
[8] Univ Creteil Univ Paris Val de Marne, Fac Med, Clin Ophtalmol, Creteil, France
[9] Univ Verona, Osped Civile Maggiore, Clin Oculist, I-37100 Verona, Italy
[10] Aristotle Univ Thessaloniki, Ahepa Univ Hosp, Sch Med, Dept Ophthalmol, GR-54006 Thessaloniki, Greece
[11] Univ Miguel Hernandez, Elche, Spain
关键词
macular degeneration; age-related maculopathy; vision loss; elderly persons; UVR exposure; antioxidants; risk factors; quality of life; research protocol;
D O I
10.1076/opep.11.2.117.28160
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
PURPOSE The aims of the EUREYE study are to evaluate the prevalence of age-related maculopathy (ARM), including macular degeneration (AMD), in elderly European populations, to investigate risk especially solar radiation and diet, and to factors for ARM and AMD, measure the impact of these conditions on vision-related quality of life. METHODS A population-based cross-sectional study with retrospective and current exposure measurements. Risk factor assessment is via questionnaires (for lifestyle factors such as smoking and alcohol, dietary risk factors, outdoor exposure) and blood analysis. Participants are people aged 65 and over. The study is carried out in 7 centres with locations spanning north to south Europe. The main outcome measure is grading of fundus photographs (for stage and type of ARM, using the International ARM Epidemiological Study Group grading system).
引用
收藏
页码:117 / 129
页数:13
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