A gold-catalyzed domino process to the steroid framework

被引:47
作者
Hildebrandt, Dirk [1 ]
Dyker, Gerald [1 ]
机构
[1] Ruhr Univ Bochum, Fak Chem 1, D-44780 Bochum, Germany
关键词
D O I
10.1021/jo060606r
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The facile formation of the B and C ring of rac-desoxyequilenin and of a chrysenone derivative in just one preparative step is demonstrated, applying a gold-catalyzed domino process, which involves a benzopyrylium cation as the key intermediate and an intramolecular [3+2] cycloaddition as the key step.
引用
收藏
页码:6728 / 6733
页数:6
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