Mouse BTEB3, a new member of the basic transcription element binding protein (BTEB) family, activates expression from GC-rich minimal promoter regions

被引：35

作者：

Martin, KM ^{[1
]}

Cooper, WN ^{[1
]}

Metcalfe, JC ^{[1
]}

Kemp, PR ^{[1
]}

机构：

[1] Univ Cambridge, Dept Biochem, Sect Cardiovasc Biol, Cambridge CB2 1QW, England

来源：

BIOCHEMICAL JOURNAL | 2000年 / 345卷

关键词：

basal transcription element; GC box; SM22 alpha promoter; SV40; promoter; transcription factor;

D O I：

10.1042/0264-6021:3450529

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Members of the three-zinc-finger family of transcription factors play an important role in determining basal transcription. We have cloned mouse BTEB3 (mBTEB3), a new member of the basic transcription element binding protein (BTEB) family, which is expressed in a wide variety of tissues. mBTEB3 activates transcription of the simian virus 40 early promoter (4-fold) and of the tissue-specific SM22 alpha promoter (100-fold), suggesting that, like BTEB1 and Spl, mBTEB3 is a basal transcription factor.

引用

页码：529 / 533

页数：5

共 18 条

[1] TRANSCRIPTION OF THE PROMOTER OF THE RAT NF-1 GENE DEPENDS ON THE INTEGRITY OF AN SP1 RECOGNITION SITE [J].

AMMENDOLA, R ;

GOUNARI, F ;

PIAGGIO, G ;

DESIMONE, V ;

CORTESE, R .

MOLECULAR AND CELLULAR BIOLOGY, 1990, 10 (01) :387-390

[2]

Biesiada E, 1999, MOL CELL BIOL, V19, P2577

[3]

BRIGGS M, 1986, SCIENCE, V324, P47

[4] BIDIRECTIONAL SV40 TRANSCRIPTION MEDIATED BY TANDEM SP1 BINDING INTERACTIONS [J].

GIDONI, D ;

KADONAGA, JT ;

BARRERASALDANA, H ;

TAKAHASHI, K ;

CHAMBON, P ;

TJIAN, R .

SCIENCE, 1985, 230 (4725) :511-517

[5]

Hautmann MB, 1997, J BIOL CHEM, V272, P10948

[6] 2 REGULATORY PROTEINS THAT BIND TO THE BASIC TRANSCRIPTION ELEMENT (BTE), A GC BOX SEQUENCE IN THE PROMOTER REGION OF THE RAT P-4501A1 GENE [J].

IMATAKA, H ;

SOGAWA, K ;

YASUMOTO, K ;

KIKUCHI, Y ;

SASANO, K ;

KOBAYASHI, A ;

HAYAMI, M ;

FUJIIKURIYAMA, Y .

EMBO JOURNAL, 1992, 11 (10) :3663-3671

[7] BINDING OF THE SPL TRANSCRIPTION FACTOR BY THE HUMAN HARVEY RASL-PROTO-ONCOGENE PROMOTER [J].

ISHII, S ;

KADONAGA, JT ;

TJIAN, R ;

BRADY, JN ;

MERLINO, GT ;

PASTAN, I .

SCIENCE, 1986, 232 (4756) :1410-1413

[8]

Kao WY, 1997, J CELL BIOCHEM, V65, P231, DOI 10.1002/(SICI)1097-4644(199705)65:2<231::AID-JCB8>3.0.CO

[9]

2-V

[10] M-CAT, CARG, AND SP1 ELEMENTS ARE REQUIRED FOR ALPHA(1)-ADRENERGIC INDUCTION OF THE SKELETAL ALPHA-ACTIN PROMOTER DURING CARDIAC MYOCYTE HYPERTROPHY - TRANSCRIPTIONAL ENHANCER FACTOR-I AND PROTEIN-KINASE-C AS CONSERVED TRANSDUCERS OF THE FETAL PROGRAM IN CARDIAC GROWTH [J].

KARNS, LR ;

KARIYA, K ;

SIMPSON, PC .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (01) :410-417

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