Update in Diagnosis and Treatment of Diabetic Foot Infections

被引:14
作者
Miller, Andy O. [1 ]
Henry, Michael [1 ]
机构
[1] Bronx Lebanon Hosp Ctr, Dept Med, Div Infect Dis, Bronx, NY 10457 USA
关键词
Diabetic foot ulcer; Diabetic foot infection; Review; Osteomyelitis; Diabetes; Antibiotics; ERYTHROCYTE SEDIMENTATION-RATE; RANDOMIZED CONTROLLED-TRIAL; VACUUM-ASSISTED-CLOSURE; PRESSURE WOUND THERAPY; CHRONIC OSTEOMYELITIS; UNDERLYING OSTEOMYELITIS; NONSURGICAL MANAGEMENT; ANTIMICROBIAL THERAPY; SURGICAL-TREATMENT; MULTICENTER TRIAL;
D O I
10.1016/j.pmr.2009.06.007
中图分类号
R49 [康复医学];
学科分类号
100232 [康复医学];
摘要
Foot infections are a major cause of morbidity and mortality in diabetics. Evaluation of diabetic foot infections often requires clinical, radiologic, laboratory, and microbiologic assessment. Osteomyelitis has a profound impact on the prognosis and management of these infections, and diagnosis can be difficult; the gold standard remains bone biopsy. Despite a panoply of studies, the optimal management of diabetic foot infections remains poorly understood. Antibiotics, surgery, rehabilitation and/or off-loading, and glycemic control remain the cornerstones of treatment; alternative therapies remain largely unproven.
引用
收藏
页码:611 / +
页数:16
相关论文
共 68 条
[1]
[Anonymous], 2002, MORB MORTAL WKLY, V51, P902
[2]
Outcomes of surgical treatment of diabetic foot osteomyelitis:: a series of 185 patients with histopathological confirmation of bone involvement [J].
Aragon-Sanchez, F. J. ;
Cabrera-Galvan, J. J. ;
Quintana-Marrero, Y. ;
Hernandez-Herrero, M. J. ;
Lazaro-Martinez, J. L. ;
Garcia-Morales, E. ;
Beneit-Montesinos, J. V. ;
Armstrong, D. G. .
DIABETOLOGIA, 2008, 51 (11) :1962-1970
[3]
Armstrong D G, 1996, J Foot Ankle Surg, V35, P280
[4]
Negative pressure wound therapy after partial diabetic foot amputation: a multicentre, randomised controlled trial [J].
Armstrong, DG ;
Lavery, LA .
LANCET, 2005, 366 (9498) :1704-1710
[5]
Value of white blood cell count with differential in the acute diabetic foot infection [J].
Armstrong, DG ;
Perales, TA ;
Murff, RT ;
Edelson, GW ;
Welchon, JG .
JOURNAL OF THE AMERICAN PODIATRIC MEDICAL ASSOCIATION, 1996, 86 (05) :224-227
[6]
ARMSTRONG DG, 1996, J AM PODIAT MED ASSN, V86, P14
[7]
ARMSTRONG DG, 1996, J FOOT ANKLE SURG, V35, P14
[8]
BAAL JG, 2004, CLIN INFECT DIS S2, V39, pS123
[9]
Diabetic foot osteomyetitis: a progress report on diagnosis and a systematic review of treatment [J].
Berendt, A. R. ;
Peters, E. J. G. ;
Bakker, K. ;
Embil, J. M. ;
Eneroth, M. ;
Hinchliffe, R. J. ;
Jeffcoate, W. J. ;
Lipsky, B. A. ;
Senneville, E. ;
Teh, J. ;
Valk, G. D. .
DIABETES-METABOLISM RESEARCH AND REVIEWS, 2008, 24 :S145-S161
[10]
Comparison of negative pressure wound therapy using vacuum-assisted closure with advanced moist wound therapy in the treatment of diabetic foot ulcers: A multicenter randomized controlled trial [J].
Blume, Peter A. ;
Walters, Jodi ;
Payne, Wyatt ;
Ayala, Jose ;
Lantis, John .
DIABETES CARE, 2008, 31 (04) :631-636