Green fluorescent proteins are light-induced electron donors

被引：154

作者：

Bogdanov, Alexey M. ^{[1
]}

Mishin, Alexander S. ^{[1
]}

Yampolsky, Ilia V. ^{[1
]}

Belousov, Vsevolod V. ^{[1
]}

Chudakov, Dmitriy M. ^{[1
]}

Subach, Fedor V. ^{[2
,3
]}

Verkhusha, Vladislav V. ^{[2
,3
]}

Lukyanov, Sergey ^{[1
]}

Lukyanov, Konstantin A. ^{[1
]}

机构：

[1] Shemiakin Ovchinnikov Inst Bioorgan Chem, Moscow, Russia

[2] Albert Einstein Coll Med, Dept Anat & Struct Biol, Bronx, NY 10467 USA

[3] Albert Einstein Coll Med, Gruss Lipper Biophoton Ctr, Bronx, NY 10467 USA

来源：

NATURE CHEMICAL BIOLOGY | 2009年 / 5卷 / 07期

关键词：

GFP; CHROMOPHORE; EVOLUTION; RED; PHOTOACTIVATION; DIVERSITY; ZOANTHUS; FAMILY; CORAL;

D O I：

10.1038/nchembio.174

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Proteins of the green fluorescent protein (GFP) family are well known owing to their unique biochemistry and extensive use as in vivo markers. We discovered that GFPs of diverse origins can act as light-induced electron donors in photochemical reactions with various electron acceptors, including biologically relevant ones. Moreover, via green-to-red GFP photoconversion, this process can be observed in living cells without additional treatment.

引用

页码：459 / 461

页数：3

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