Numerical investigation of the effect of blade geometry on blood trauma in a centrifugal blood pump

被引:34
作者
Chan, WK [1 ]
Wong, YW [1 ]
Ding, Y [1 ]
Chua, LP [1 ]
Yu, SCM [1 ]
机构
[1] Nanyang Technol Univ, Sch Mech & Prod Engn, Singapore 639798, Singapore
关键词
blood trauma; centrifugal blood pump; numerical simulation; computational fluid dynamics;
D O I
10.1046/j.1525-1594.2002.06954.x
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Fluid dynamic forces in centrifugal blood pump impellers are of key importance in destruction of red blood cells (RBCs) because high rotational speed leads to strong interaction between the impeller and the RBCs. In this paper, three-dimensional models of five different blade geometries are investigated numerically using the commercial software CFX-TASCflow, and the streaklines of RBCs are obtained using the Lagrangian particle tracking method. In reality, RBCs pass through the pump along complicated paths resulting in a highly irregular loading condition for each RBC. In order to enable the prediction of blood damage under the action of these complex-loading conditions, a cumulative damage model for RBCs was adopted in this paper. The numerically simulated percent hemoglobin (%HB) released as RBCs traversed the impeller and volute was examined. It was observed that the residence time of particles in the blade passage is a critical factor in determining hemolytic effects. This, in turn, is a function of the blade geometry. In addition, it was observed that the volute profile is an important influence on the computed HB% released.
引用
收藏
页码:785 / 793
页数:9
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