Antibiotic resistance gene discovery in food-producing animals

被引:70
作者
Allen, Heather K. [1 ]
机构
[1] USDA ARS, Natl Anim Dis Ctr, Food Safety & Enter Pathogens Res Unit, Ames, IA 50010 USA
关键词
SPECTRUM BETA-LACTAMASES; ESCHERICHIA-COLI; ANTIMICROBIAL RESISTANCE; SWINE; PREVALENCE; CATTLE; ENTEROBACTERIACEAE; METAGENOMICS; RESERVOIRS; SLAUGHTER;
D O I
10.1016/j.mib.2014.06.001
中图分类号
Q93 [微生物学];
学科分类号
071005 [微生物学];
摘要
Numerous environmental reservoirs contribute to the widespread antibiotic resistance problem in human pathogens. One environmental reservoir of particular importance is the intestinal bacteria of food-producing animals. In this review I examine recent discoveries of antibiotic resistance genes in agricultural animals. Two types of antibiotic resistance gene discoveries will be discussed: the use of classic microbiological and molecular techniques, such as culturing and PCR, to identify known genes not previously reported in animals; and the application of high-throughput technologies, such as metagenomics, to identify novel genes and gene transfer mechanisms. These discoveries confirm that antibiotics should be limited to prudent uses.
引用
收藏
页码:25 / 29
页数:5
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