Analysis of plasmid and chromosomal DNA of multidrug-resistant Salmonella enterica serovar typhi from Asia

被引：54

作者：

Mirza, S

Kariuki, S

Mamun, KZ

Beeching, NJ

Hart, CA

机构：

[1] Univ Liverpool, Dept Med Microbiol & Genitourinary Med, Liverpool L69 3GA, Merseyside, England

[2] Univ Liverpool, Sch Trop Med, Liverpool L69 3GA, Merseyside, England

[3] Armed Forces Inst Pathol, Washington, DC 20306 USA

[4] Kenya Med Res Inst, Ctr Microbiol Res, Nairobi, Kenya

[5] Dhaka Med Coll, Dhaka, Bangladesh

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2000年 / 38卷 / 04期

基金：

英国惠康基金;

关键词：

D O I：

10.1128/JCM.38.4.1449-1452.2000

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Molecular analysis of chromosomal DNA from 193 multidrug-resistant (MDR) Salmonella enterica serovar Typhi isolates from 1990 to 1995 from Pakistan, Kuwait, Malaysia, Bangladesh, and India produced a total of five major different pulsed-field gel electrophoresis (PFGE) patterns. Even within a particular country MDR S, enterica serovar Typhi DNA was found to be in different PFGE groups. Similar self-transferable 98-MDa plasmids belonging to either incompatibility group incHI1 or incHI1/FIIA were implicated in the MDR phenotype in S. enterica serovar Typhi isolates from all the locations except Quetta, Pakistan, where the majority were of incFIA. A total of five different PFGE genotypes with six different plasmids, based on incompatibility and restriction endonuclease analysis groups, were found among these MDR S. enterica serovar Typhi isolates.

引用

页码：1449 / 1452

页数：4

共 28 条

[1] PROBLEM AND IMPLICATIONS OF CHLORAMPHENICOL RESISTANCE IN TYPHOID BACILLUS [J].