Isolation and Purification of Geniposide, Crocin-1, and Geniposidic Acid from the Fruit of Gardenia jasminoides Ellis by High-Speed Counter-Current Chromatography

被引：24

作者：

Liang, Zhikun ^{[1
,2
]}

Yang, Mei ^{[1
,2
]}

Xu, Xinjun ^{[1
,2
]}

Xie, Zhisheng ^{[1
,2
]}

Huang, Jieyun ^{[1
,2
]}

Li, Xinying ^{[1
,2
]}

Yang, Depo ^{[1
,2
]}

机构：

[1] Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou 510006, Guangdong, Peoples R China

[2] Guangdong Technol Res Ctr Adv Chinese Med, Guangzhou, Guangdong, Peoples R China

来源：

SEPARATION SCIENCE AND TECHNOLOGY | 2014年 / 49卷 / 09期

关键词：

Gardenia jasminoides Ellis; high-speed counter-current chromatography; geniposide; crocin-1; geniposidic acid; SEPARATION;

D O I：

10.1080/01496395.2013.879179

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

Geniposide, crocin-1, and geniposidic acid were simultaneously separated from the fruit of Gardenia jasminoides Ellis by one step of high-speed counter-current chromatography with the solvent system composed of ethyl acetate-n-butanol-water(1:4:5, v/v/v) within 130 min. The purities of the three compounds were 98.7%, 97.1%, and 90.4%, respectively, as determined by HPLC. Their structures were confirmed by MS, UV, H-1 NMR, and(13)C NMR analysis.

引用

页码：1427 / 1433

页数：7

共 20 条

[1]

Bi ZhiMing Bi ZhiMing, 2008, Chemistry and Industry of Forest Products, V28, P67

[2]

Cheng H. L., 2004, ANHUI MED PHARM J, V8, P167, DOI DOI 10.3969/J.ISSN.1009-6469.2004.03.003

[3]

Committee of National Pharmacopoeia, 2010, PHARMACOPOEIA PEOPLE

[4]

Separation of alkaloids from herbs using high-speed counter-current chromatography [J].