Segmentation of Head and Neck Lymph Node Regions for Radiotherapy Planning Using Active Contour-Based Atlas Registration

被引:49
作者
Gorthi, Subrahmanyam [1 ]
Duay, Valerie [2 ]
Houhou, Nawal [1 ]
Cuadra, Meritxell Bach [1 ]
Schick, Ulrike [3 ]
Becker, Minerva [3 ]
Allal, Abdelkarim S. [3 ]
Thiran, Jean-Philippe [1 ]
机构
[1] Ecole Polytech Fed Lausanne EPFL, Signal Proc Lab LTS5, Lausanne, Switzerland
[2] Univ Appl Sci Western Switzerland HES SO Geneve, Inst Bioengn, Geneva, Switzerland
[3] Univ Hosp Geneva, Dept Radiat Oncol, Geneva, Switzerland
关键词
Atlas-based segmentation; head and neck; IMRT; lymph node regions; non-rigid registration; radiotherapy; IMAGE REGISTRATION; PERFORMANCE; DELINEATION; VALIDATION; ALGORITHM;
D O I
10.1109/JSTSP.2008.2011104
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
080906 [电磁信息功能材料与结构]; 082806 [农业信息与电气工程];
摘要
In this paper, we present the segmentation of the head and neck lymph node regions using a new active contour-based atlas registration model. We propose to segment the lymph node regions without directly including them in the atlas registration process; instead, they are segmented using the dense deformation field computed from the registration of the atlas structures with distinct boundaries. This approach results in robust and accurate segmentation of the lymph node regions even in the presence of significant anatomical variations between the atlas-image and the patient's image to be segmented. We also present a quantitative evaluation of lymph node regions segmentation using various statistical as well as geometrical metrics: sensitivity, specificity, dice similarity coefficient and Hausdorff distance. A comparison of the proposed method with two other state of the art methods is presented. The robustness of the proposed method to the atlas selection, in segmenting the lymph node regions, is also evaluated.
引用
收藏
页码:135 / 147
页数:13
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