Asymmetric functionalization of a chiral non-racemic oxazolidine ester enolate. A new route towards the preparation of quaternary serine esters

被引：15

作者：

Alezra, V

Bonin, M

Chiaroni, A

Micouin, L

Riche, C

Husson, HP

机构：

[1] CNRS, Chim Therapeut Lab, F-75270 Paris 06, France

[2] Univ Paris 05, UMR 8638, Fac Sci Pharmaceut & Biol, F-75270 Paris, France

[3] Inst Chim Substances Nat, F-91198 Gif Sur Yvette, France

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 11期

关键词：

D O I：

10.1016/S0040-4039(00)00026-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new route towards the preparation of enantiomerically pure quaternary serine esters is described. The key step involves the diastereoselective functionalization of an oxazolidine ester enolate having an exocyclic chiral appendage. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：1737 / 1740

页数：4

共 11 条

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