A supramolecular ion channel based on amphiphilic cholic acid derivatives

被引：22

作者：

Kobuke, Y

Nagatani, T

机构：

[1] Nara Inst Sci & Technol, Grad Sch Mat Sci, Nara 6300101, Japan

[2] Shizuoka Univ, Fac Engn, Hamamatsu, Shizuoka 4328514, Japan

来源：

CHEMISTRY LETTERS | 2000年 / 04期

关键词：

D O I：

10.1246/cl.2000.298

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Cholic acid was modified so as to represent the simplest expression of an artificial supramolecular ion channel by converting three hydroxyls to methyl ethers and a carboxyl to a methylene(trimethyl)ammonium grouping. It gave stable single channel currents showing several conductance values in planar bilayer lipid membrane.

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页码：298 / 299

页数：2

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