The role of interleukin 15 in mounting an immune response against microbial infections

被引：37

作者：

Yoshikai, Y ^{[1
]}

Nishimura, H ^{[1
]}

机构：

[1] Nagoya Univ, Sch Med, Dis Mechanism & Control Res Inst, Lab Host Def & Germfree Life, Nagoya, Aichi 466, Japan

来源：

MICROBES AND INFECTION | 2000年 / 2卷 / 04期

关键词：

IL-15; NK cells; gamma delta T cells; CD8 T cells; protection; infection; bacteria; virus;

D O I：

10.1016/S1286-4579(00)00329-4

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Interleukin (IL)-15 is a recently described cytokine that resembles IL-2 in its biological activities, stimulating natural killer cells, T cells and B cells to proliferate, secrete cytokines, and exhibit increased cytotoxicities or produce antibody IL-15 also exerts unique functions such as stimulation of phagocytes, maintenance of mast cells and migration of activated/memory T cells. IL-15 is involved in protection against infections with a variety of microbes through not only activating innate immunity but also mounting adaptive immunity. (C) 2000 Editions scientifiques et medicales Elsevier SAS.

引用

页码：381 / 389

页数：9

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