DNA stress checkpoint control and plant development

被引：89

作者：

Cools, Toon ^{[1
,2
]}

De Veylder, Lieven ^{[1
,2
]}

机构：

[1] Univ Ghent VIB, Dept Plant Syst Biol, B-9052 Ghent, Belgium

[2] Univ Ghent, Dept Mol Genet, B-9052 Ghent, Belgium

来源：

CURRENT OPINION IN PLANT BIOLOGY | 2009年 / 12卷 / 01期

关键词：

CELL-CYCLE CHECKPOINT; TOPOISOMERASE-VI COMPLEX; GENOTOXIC STRESS; GENOME INSTABILITY; GENE-EXPRESSION; ARABIDOPSIS; DAMAGE; ATR; RESPONSES; ENDOREDUPLICATION;

D O I：

10.1016/j.pbi.2008.09.012

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Plants are sedentary, and so have unavoidably close contact with agents that target their genome integrity. To sense and react to these threats, plants have evolved DNA stress checkpoint mechanisms that arrest the cell cycle and activate the DNA repair machinery to preserve the genome content. Although the pathways that maintain DNA integrity are largely conserved among eukaryotic organisms, plants put different accents on cell cycle control under DNA stress and might have their own way to cope with it.

引用

页码：23 / 28

页数：6

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