On characterization of DNA primary sequences by a condensed matrix

被引:63
作者
Randic, M [1 ]
机构
[1] Natl Inst Chem, Ljubljana 1001, Slovenia
关键词
D O I
10.1016/S0009-2614(99)01321-4
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
The proliferation of reports on the primary DNA sequences introduces the problem of digesting such information. We consider a condensed characterization of primary sequences of DMA based on 4 X 4 matrices the row and columns of which are associated with the four nucleic bases A, G, C and T. The condensed matrices for the primary sequences of DNA can serve as a source of sequence invariants that would allow quantitative comparisons of DNA from different sources. The approach is outlined on a particular human beta-globin sequence extract. (C) 2000 Elsevier Science. B.V. All rights reserved.
引用
收藏
页码:29 / 34
页数:6
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