From protein sequence to function

被引：27

作者：

Danchin, A ^{[1
]}

机构：

[1] Inst Pasteur, F-75724 Paris 15, France

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1999年 / 9卷 / 03期

关键词：

D O I：

10.1016/S0959-440X(99)80049-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

As genome sequences and protein structures are deciphered, we wish to predict their corresponding functions. Many functions cannot be told from the sequence, however, although there has been progress in this quest for an impossible Grail. Furthermore, a structure and its corresponding sequence become most interesting when one knows the function. Inductive reasoning, based on the integration of biological and sequence knowledge, should enable sequence and functional data to be combined in a productive way.

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收藏

页码：363 / 367

页数：5

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