Connectivities and synchronous firing in cortical neuronal networks

被引:32
作者
Jia, LC
Sano, M
Lai, PY
Chan, CK [1 ]
机构
[1] Acad Sinica, Inst Phys, Taipei 115, Taiwan
[2] Univ Tokyo, Dept Phys, Bunkyo Ku, Tokyo 1130033, Japan
[3] Natl Cent Univ, Dept Phys, Chungli 320, Taiwan
[4] Natl Cent Univ, Ctr Complex Syst, Chungli 320, Taiwan
[5] Yuanpei Univ Sci & Technol, Inst Med Image, Hsinchu 300, Taiwan
关键词
D O I
10.1103/PhysRevLett.93.088101
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
Network connectivities ((k) over bar) of cortical neural cultures are studied by synchronized firing and determined from measured correlations between fluorescence intensities of firing neurons. The bursting frequency (f) during synchronized firing of the networks is found to be an increasing function of (k) over bar. With f taken to be proportional to (k) over bar, a simple random model with a (k) over bar dependent connection probability p((k) over bar) has been constructed to explain our experimental findings successfully.
引用
收藏
页码:088101 / 1
页数:4
相关论文
共 19 条
[1]   Experimental analysis of neuronal dynamics in cultured cortical networks and transitions between different patterns of activity [J].
Canepari, M ;
Bove, M ;
Maeda, E ;
Cappello, M ;
Kawana, A .
BIOLOGICAL CYBERNETICS, 1997, 77 (02) :153-162
[2]   PATTERN-FORMATION OUTSIDE OF EQUILIBRIUM [J].
CROSS, MC ;
HOHENBERG, PC .
REVIEWS OF MODERN PHYSICS, 1993, 65 (03) :851-1112
[3]  
Haken H., 1996, PRINCIPLES BRAIN FUN
[4]   Learning-induced synchronization of a globally coupled excitable map system [J].
Hayakawa, Y ;
Sawada, Y .
PHYSICAL REVIEW E, 2000, 61 (05) :5091-5097
[5]  
HUGH PC, 1993, J NEUROPHYSIOL, V70, P1606
[6]  
KANDEL ER, 1997, PRINCIPLES NEURAL SC
[7]   Systems biology: A brief overview [J].
Kitano, H .
SCIENCE, 2002, 295 (5560) :1662-1664
[8]   NEURONAL NETWORKS WITH SPONTANEOUS, CORRELATED BURSTING ACTIVITY - THEORY AND SIMULATIONS [J].
KOWALSKI, JM ;
ALBERT, GL ;
RHOADES, BK ;
GROSS, GW .
NEURAL NETWORKS, 1992, 5 (05) :805-822
[9]  
LANDAU LJ, 1999, CONCEPTS NEURAL NETW, P36126
[10]   FUNCTIONAL SYNAPSE FORMATION BETWEEN CULTURED NEURONS OF RAT CEREBRAL-CORTEX - BLOCK BY A PROTEIN-KINASE INHIBITOR WHICH DOES NOT PERMEATE THE CELL-MEMBRANE [J].
MURAMOTO, K ;
KOBAYASHI, K ;
NAKANISHI, S ;
MATSUDA, Y ;
KURODA, Y .
PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES, 1988, 64 (10) :319-322