Understanding and controlling the cell cycle with natural products

被引：183

作者：

Hung, DT

Jamison, TF

Schreiber, SL

机构：

[1] Howard Hughes Medical Institute, Dept. of Chem. and Chemical Biology, Harvard University, Cambridge

来源：

CHEMISTRY & BIOLOGY | 1996年 / 3卷 / 08期

关键词：

D O I：

10.1016/S1074-5521(96)90129-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Small molecule natural products have aided in the discovery and characterization of many proteins critical to the progression and maintenance of the cell cycle. Identification of the direct target of a natural product gives scientists a tool to control a specific aspect of the cell cycle, thus facilitating the study of the cell-cycle machinery.

引用

收藏

页码：623 / 639

页数：17

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