Imaging and Laboratory Biomarkers in Cardiovascular Disease

被引：9

作者：

Andreassi, Maria Grazia ^{[1
,2
]}

Gastaldelli, Amalia ^{[1
,2
]}

Clerico, Aldo

Salvadori, Piero A. ^{[1
,2
]}

Sicari, Rosa ^{[1
,2
]}

Picano, Eugenio ^{[1
,2
]}

机构：

[1] CNR, Inst Clin Physiol, I-56124 Pisa, Italy

[2] Fdn Toscana Gabriele Monasterio, Pisa, Italy

来源：

CURRENT PHARMACEUTICAL DESIGN | 2009年 / 15卷 / 10期

关键词：

Atherosclerosis; biomarkers; cost; risk; POSITRON-EMISSION-TOMOGRAPHY; GAMMA-GLUTAMYL-TRANSFERASE; CORONARY-ARTERY-DISEASE; ULTRASOUND LUNG COMETS; STRESS ECHOCARDIOGRAPHY; MYOCARDIAL-INFARCTION; COMPUTED-TOMOGRAPHY; MAGNETIC-RESONANCE; RISK STRATIFICATION; RADIATION-EXPOSURE;

D O I：

10.2174/138161209787846937

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Imaging and laboratory biomarkers are an essential support to modern practice of medicine, allowing a better identification, severity titration, staging and follow-up of atherosclerosis and heart failure disease. This review provides an overview of imaging, biochemical and genetic biomarkers used in clinical practice and for research purposes in order to evaluate the 4 different aspect of patient vulnerability to cardiovascular disease: arterial; blood; myocardial; metabolic vulnerability. Yet, no single perfect biomarker exists and there is wide room for optimization and integration between clinical evaluation and biomarker evaluation. In general, a targeted approach tailored on the individual patient should be preferred to a carpet diagnostic bombing, which will lead to an exorbitant multiplier of costs, risks and inappropriate testing.

引用

页码：1131 / 1141

页数：11

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