Structures of acylated sucroses from the flower buds of Prunus mume

被引:24
作者
Fujimoto, Katsuyoshi [1 ]
Nakamura, Seikou [1 ]
Matsumoto, Takahiro [1 ]
Ohta, Tomoe [1 ]
Yoshikawa, Masayuki [1 ]
Ogawa, Keiko [1 ]
Kashiwazaki, Eri [1 ]
Matsuda, Hisashi [1 ]
机构
[1] Kyoto Pharmaceut Univ, Dept Pharmacognosy, Yamashina Ku, Kyoto 6078412, Japan
基金
日本学术振兴会;
关键词
Prunus mume; Mumeose; Acylated sucrose; Aldose reductase; Medicinal flower; MACROPHYLLA VAR. THUNBERGII; ALDOSE REDUCTASE INHIBITORS; CHINESE NATURAL MEDICINES; CAMELLIA-JAPONICA; OLEANANE-TYPE; BIOACTIVE CONSTITUENTS; TRITERPENE SAPONINS; MELANOGENESIS; GLYCOSIDES; OLIGOGLYCOSIDES;
D O I
10.1007/s11418-014-0818-z
中图分类号
R914 [药物化学];
学科分类号
100705 [微生物与生化药学];
摘要
Seven new acylated sucroses, mumeoses P-V, were isolated from the flower buds of Prunus mume, cultivated in Zhejiang province, China. Their chemical structures were elucidated on the basis of chemical and physicochemical evidence. Moreover, mumeoses C, D, and R, were shown to substantially inhibit aldose reductase.
引用
收藏
页码:481 / 487
页数:7
相关论文
共 20 条
[1]
Fujimoto K, 2013, CHEM PHARM BULL, V61, P445, DOI 10.1248/cpb.c12-01068
[2]
Medicinal Flowers. XXXV. Nor-Oleanane-Type and Acylated Oleanane-Type Triterpene Saponins from the Flower Buds of Chinese Camellia japonica and Their Inhibitory Effects on Melanogenesis [J].
Fujimoto, Katsuyoshi ;
Nakamura, Seikou ;
Nakashima, Souichi ;
Matsumoto, Takahiro ;
Uno, Kaoru ;
Ohta, Tomoe ;
Miura, Tomoko ;
Matsuda, Hisashi ;
Yoshikawa, Masayuki .
CHEMICAL & PHARMACEUTICAL BULLETIN, 2012, 60 (09) :1188-1194
[3]
Medicinal Flowers. XXXX. Structures of Dihydroisocoumarin Glycosides and Inhibitory Effects on Aldose Reducatase from the Flowers of Hydrangea macrophylla var. thunbergii [J].
Liu, Jiang ;
Nakamura, Seikou ;
Zhuang, Yan ;
Yoshikawa, Masayuki ;
Hussein, Ghazi Mohamed Eisa ;
Matsuo, Kyohei ;
Matsuda, Hisashi .
CHEMICAL & PHARMACEUTICAL BULLETIN, 2013, 61 (06) :655-661
[4]
Hydrangeamines A and B, novel polyketide-type pseudoalkaloid-coupled secoiridoid glycosides from the flowers of Hydrangea macrophylla var. thunbergii [J].
Liu, Jiang ;
Nakamura, Seikou ;
Matsuda, Hisashi ;
Yoshikawa, Masayuki .
TETRAHEDRON LETTERS, 2013, 54 (01) :32-34
[5]
Matsuda H, 2003, CHEM PHARM BULL, V51, P440, DOI 10.1248/cpb.51.440
[6]
Medicinal flowers.: VI.: Absolute stereostructures of two new flavanone glycosides and a phenylbutanoid glycoside from the flowers of Chrysanthemum indicum L.:: Their inhibitory activities for rat lens aldose reductase [J].
Matsuda, H ;
Morikawa, T ;
Toguchida, I ;
Harima, S ;
Yoshikawa, M .
CHEMICAL & PHARMACEUTICAL BULLETIN, 2002, 50 (07) :972-975
[7]
Structural requirements of flavonoids and related compounds for aldose reductase inhibitory activity [J].
Matsuda, H ;
Morikawa, T ;
Toguchida, I ;
Yoshikawa, M .
CHEMICAL & PHARMACEUTICAL BULLETIN, 2002, 50 (06) :788-795
[8]
Medicinal Flowers. XXXIII. Anti-hyperlipidemic and Anti-hyperglycemic Effects of Chakasaponins I-III and Structure of Chakasaponin IV from Flower Buds of Chinese Tea Plant (Camellia sinensis) [J].
Matsuda, Hisashi ;
Hamao, Makoto ;
Nakamura, Seikou ;
Kon'i, Haruka ;
Murata, Megumi ;
Yoshikawa, Masayuki .
CHEMICAL & PHARMACEUTICAL BULLETIN, 2012, 60 (05) :674-680
[9]
Antidiabetogenic Constituents from the Thai Traditional Medicine Cotylelobium melanoxylon [J].
Matsuda, Hisashi ;
Asao, Yasunobu ;
Nakamura, Seikou ;
Hamao, Makoto ;
Sugimoto, Sachiko ;
Hongo, Masako ;
Pongpiriyadacha, Yutana ;
Yoshikawa, Masayuki .
CHEMICAL & PHARMACEUTICAL BULLETIN, 2009, 57 (05) :487-494
[10]
Structures of new friedelane-type triterpenes and eudesmane-type sesquiterpene and aldose reductase inhibitors from Salacia chinensis [J].
Morikawa, T ;
Kishi, A ;
Pongpiriyadacha, Y ;
Matsuda, H ;
Yoshikawa, M .
JOURNAL OF NATURAL PRODUCTS, 2003, 66 (09) :1191-1196