Natriuretic Peptides in Heart Failure with Preserved Ejection Fraction

被引：34

作者：

Richards, A. Mark ^{[1
,2
]}

Januzzi, James L., Jr. ^{[3
]}

Troughton, Richard W. ^{[2
]}

机构：

[1] Natl Univ Singapore, Natl Univ Heart Ctr, Cardiovasc Res Inst, Dept Cardiac, Singapore 119228, Singapore

[2] Univ Otago, Christchurch Heart Inst, Dept Med, Christchurch 8140, New Zealand

[3] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Cardiac Intens Care Unit, Boston, MA 02114 USA

来源：

HEART FAILURE CLINICS | 2014年 / 10卷 / 03期

关键词：

Heart failure; Cardiac natriuretic peptides; B-type natriuretic peptide; N-terminal prohormone B-type natriuretic peptide; Diagnosis; Prognosis; LEFT-VENTRICULAR DYSFUNCTION; RANDOMIZED CONTROLLED-TRIAL; EMERGENCY-DEPARTMENT PRIDE; STANDARD MEDICAL THERAPY; SYSTOLIC FUNCTION; DIASTOLIC FUNCTION; EUROPEAN-SOCIETY; PROGNOSTIC VALUE; ELDERLY-PATIENTS; TERMINAL PROBNP;

D O I：

10.1016/j.hfc.2014.04.006

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Timely diagnosis, early introduction of appropriate treatment, accurate risk stratification, and optimal titration of therapy are all key to the management of acute and chronic heart failure (HF). Plasma concentrations of the cardiac natriuretic peptides (NPs) are valuable aids in each of these elements of care. However, most data are derived from cohorts with undifferentiated HF or HF with reduced ejection fraction (HFREF), and the performance and best application of NPs in HF with preserved ejection fraction (HFPEF) is less certain. This review outlines the evidence for use of NPs in the evaluation and management of HFPEF.

引用

页码：453 / +

页数：20

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