Successful eradication of Helicobacter pylori as determined by 13C-urea breath test does not alter fibrinogen and acute phase response markers

In this study we examined in 100 patients testing positive for Helicobacter pylori infection whether successful eradication therapy with pantoprazole, clarithromycin, and metronidazole alters fibrinogen and other acute phase response markers. Of 100 patients, only 11 showed a fibrinogen level above 300 mg/dL, Successful eradication proven by the C-13-urea breath test does not alter acute phase response markers. These findings indicate that Helicobacter pylori infection is unlikely to affect atherosclerosis unfavourably via acute phase response. (C) 2000 Elsevier Science Ltd. All rights reserved.