Straightforward biodegradable nanoparticle generation through megahertz-order ultrasonic atomization

被引：24

作者：

Forde, Gareth M. ^{[1
]}

Friend, James ^{[1
]}

Williamson, Tom ^{[1
]}

机构：

[1] Monash Univ, Clayton, Vic 3800, Australia

来源：

APPLIED PHYSICS LETTERS | 2006年 / 89卷 / 06期

关键词：

D O I：

10.1063/1.2221914

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

Simple and reliable formation of biodegradable nanoparticles formed from poly-epsilon-caprolactone was achieved using 1.645 MHz piston atomization of a source fluid of 0.5% w/v of the polymer dissolved in acetone; the particles were allowed to descend under gravity in air 8 cm into a 1 mM solution of sodium dodecyl sulfate. After centrifugation to remove surface agglomerations, a symmetric monodisperse distribution of particles phi 186 nm (SD=5.7, n=6) was obtained with a yield of 65.2%. (c) 2006 American Institute of Physics.

引用

页数：3

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[2]

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