Telomerase: Anti-cancer target or just a fascinating enzyme?

被引：25

作者：

Hamilton, SE ^{[1
]}

Corey, DR ^{[1
]}

机构：

[1] UNIV TEXAS,SW MED CTR,HOWARD HUGHES MED INST,DALLAS,TX 75235

来源：

CHEMISTRY & BIOLOGY | 1996年 / 3卷 / 11期

关键词：

D O I：

10.1016/S1074-5521(96)90173-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Telomerase activity is upregulated in most types of malignant tumor. Highly selective small molecule inhibitors will be needed to understand the biological basis for this observation and to determine if telomerase is a viable target for chemotherapy.

引用

页码：863 / 867

页数：5

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