Neurexin 1 (NRXN1) Deletions in Schizophrenia

被引：171

作者：

Kirov, George ^{[1
]}

Rujescu, Dan ^{[2
]}

Ingason, Andres ^{[3
,4
]}

Collier, David A. ^{[5
]}

O'Donovan, Michael C. ^{[1
]}

Owen, Michael J. ^{[1
]}

机构：

[1] Cardiff Univ, MRC, Ctr Neuropsychiat Genet & Genom, Dept Psychol Med & Neurol,Sch Med, Cardiff CF14 4XN, S Glam, Wales

[2] Univ Munich, Dept Psychiat, Div Mol & Clin Neurobiol, D-8000 Munich, Germany

[3] Copenhagen Univ Hosp, Res Inst Biol Psychiat, Mental Hlth Ctr Sct Hans, Roskilde, Denmark

[4] DeCODE Genet, Reykjavik, Iceland

[5] Kings Coll London, Inst Psychiat, Social Genet & Dev Psychiat Ctr, London WC2R 2LS, England

来源：

SCHIZOPHRENIA BULLETIN | 2009年 / 35卷 / 05期

基金：

英国医学研究理事会;

关键词：

AUTISM SPECTRUM DISORDER; STRUCTURAL VARIANTS; GENES; DISRUPTION; RISK; LOCI; CNVS;

D O I：

10.1093/schbul/sbp079

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

[No abstract available]

引用

页码：851 / 854

页数：4

共 23 条

[1] High frequency of neurexin 1β signal peptide structural variants in patients with autism [J].

Feng, Jinong ;

Schroer, Richard ;

Yan, Jin ;

Song, Wenjia ;

Yang, Chunmei ;

Bockholt, Anke ;

Cook, Edwin H., Jr. ;

Skinner, Cindy ;

Schwartz, Charles E. ;

Sommer, Steve S. .

NEUROSCIENCE LETTERS, 2006, 409 (01) :10-13

[2] Oligonucleotide microarray analysis of genomic imbalance in children with mental retardation [J].

Friedman, J. M. ;

Baross, Agnes ;

Delaney, Allen D. ;

Ally, Adrian ;

Arbour, Laura ;

Asano, Jennifer ;

Bailey, Dione K. ;

Barber, Sarah ;

Birch, Patricia ;

Brown-John, Mabel ;

Cao, Manqiu ;

Chan, Susanna ;

Charest, David L. ;

Farnoud, Noushin ;

Fernandes, Nicole ;

Flibotte, Stephane ;

Go, Anne ;

Gibson, William T. ;

Holt, Robert A. ;

Jones, Steven J. M. ;

Kennedy, Giulia C. ;

Krzywinski, Martin ;

Langlois, Sylvie ;

Li, Haiyan I. ;

McGillivray, Barbara C. ;

Nayar, Tarun ;

Pugh, Trevor J. ;

Rajcan-Separovic, Evica ;

Schein, Jacqueline E. ;

Schnerch, Angelique ;

Siddiqui, Asim ;

Van Allen, Margot I. ;

Wilson, Gary ;

Yong, Siu-Li ;

Zahir, Farah ;

Eydoux, Patrice ;

Marra, Marco A. .

AMERICAN JOURNAL OF HUMAN GENETICS, 2006, 79 (03) :500-513

[3] Autism genome-wide copy number variation reveals ubiquitin and neuronal genes [J].

Glessner, Joseph T. ;

Wang, Kai ;

Cai, Guiqing ;

Korvatska, Olena ;

Kim, Cecilia E. ;

Wood, Shawn ;

Zhang, Haitao ;

Estes, Annette ;

Brune, Camille W. ;

Bradfield, Jonathan P. ;

Imielinski, Marcin ;

Frackelton, Edward C. ;

Reichert, Jennifer ;

Crawford, Emily L. ;

Munson, Jeffrey ;

Sleiman, Patrick M. A. ;

Chiavacci, Rosetta ;

Annaiah, Kiran ;

Thomas, Kelly ;

Hou, Cuiping ;

Glaberson, Wendy ;

Flory, James ;

Otieno, Frederick ;

Garris, Maria ;

Soorya, Latha ;

Klei, Lambertus ;

Piven, Joseph ;

Meyer, Kacie J. ;

Anagnostou, Evdokia ;

Sakurai, Takeshi ;

Game, Rachel M. ;

Rudd, Danielle S. ;

Zurawiecki, Danielle ;

McDougle, Christopher J. ;

Davis, Lea K. ;

Miller, Judith ;

Posey, David J. ;

Michaels, Shana ;

Kolevzon, Alexander ;

Silverman, Jeremy M. ;

Bernier, Raphael ;

Levy, Susan E. ;

Schultz, Robert T. ;

Dawson, Geraldine ;

Owley, Thomas ;

McMahon, William M. ;

Wassink, Thomas H. ;

Sweeney, John A. ;

Nurnberger, John I., Jr. ;

Coon, Hilary .

NATURE, 2009, 459 (7246) :569-573

[4] Disruption of neurexin 1 associated with autism spectrum disorder [J].

Kim, Hyung-Goo ;

Kishikawa, Shotaro ;

Higgins, Anne W. ;

Seong, Ihn-Sik ;

Donovan, Diana J. ;

Shen, Yiping ;

Lally, Eric ;

Weiss, Lauren A. ;

Najm, Juliane ;

Kutsche, Kerstin ;

Descartes, Maria ;

Holt, Lynn ;

Braddock, Stephen ;

Troxell, Robin ;

Kaplan, Lee ;

Volkmar, Fred ;

Klin, Ami ;

Tsatsanis, Katherine ;

Harris, David J. ;

Noens, Ilse ;

Pauls, David L. ;

Daly, Mark J. ;

MacDonald, Marcy E. ;

Morton, Cynthia C. ;

Quade, Bradley J. ;

Gusella, James E. .

AMERICAN JOURNAL OF HUMAN GENETICS, 2008, 82 (01) :199-207

[5] Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia [J].

Kirov, George ;

Gumus, Dilihan ;

Chen, Wei ;

Norton, Nadine ;

Georgieva, Lyudmila ;

Sari, Murat ;

O'Donovan, Michael C. ;

Erdogan, Fikret ;

Owen, Michael J. ;

Ropers, Hans-Hilger ;

Ullmann, Reinhard .

HUMAN MOLECULAR GENETICS, 2008, 17 (03) :458-465

[6] Support for the involvement of large copy number variants in the pathogenesis of schizophrenia [J].

Kirov, George ;

Grozeva, Detelina ;

Norton, Nadine ;

Ivanov, Dobril ;

Mantripragada, Kiran K. ;

Holmans, Peter ;

Craddock, Nick ;

Owen, Michael J. ;

O'Donovan, Michael C. .

HUMAN MOLECULAR GENETICS, 2009, 18 (08) :1497-1503

[7] Genetics of autism spectrum disorders [J].

Kumar, Ravinesh A. ;

Christian, Susan L. .

CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS, 2009, 9 (03) :188-197

[8] Structural variation of chromosomes in autism spectrum disorder [J].

Marshall, Christian R. ;

Noor, Abdul ;

Vincent, John B. ;

Lionel, Anath C. ;

Feuk, Lars ;

Skaug, Jennifer ;

Shago, Mary ;

Moessner, Rainald ;

Pinto, Dalila ;

Ren, Yan ;

Thiruvahindrapduram, Bhoorna ;

Fiebig, Andreas ;

Schreiber, Stefan ;

Friedman, Jan ;

Ketelaars, Cees E. J. ;

Vos, Yvonne J. ;

Ficicioglu, Can ;

Kirkpatrick, Susan ;

Nicolson, Rob ;

Sloman, Leon ;

Surnmers, Anne ;

Gibbons, Clare A. ;

Teebi, Ahmad ;

Chitayat, David ;

Weksberg, Rosanna ;

Thompson, Ann ;

Vardy, Cathy ;

Crosbie, Vicki ;

Luscombe, Sandra ;

Baatjes, Rebecca ;

Zwaigenbaum, Lonnie ;

Roberts, Wendy ;

Fernandez, Bridget ;

Szatmari, Peter ;

Scherer, Stephen W. .

AMERICAN JOURNAL OF HUMAN GENETICS, 2008, 82 (02) :477-488

[9] Identifying autism loci and genes by tracing recent shared ancestry [J].

Morrow, Eric M. ;

Yoo, Seung-Yun ;

Flavell, Steven W. ;

Kim, Tae-Kyung ;

Lin, Yingxi ;

Hill, Robert Sean ;

Mukaddes, Nahit M. ;

Balkhy, Soher ;

Gascon, Generoso ;

Hashmi, Asif ;

Al-Saad, Samira ;

Ware, Janice ;

Joseph, Robert M. ;

Greenblatt, Rachel ;

Gleason, Danielle ;

Ertelt, Julia A. ;

Apse, Kira A. ;

Bodell, Adria ;

Partlow, Jennifer N. ;

Barry, Brenda ;

Yao, Hui ;

Markianos, Kyriacos ;

Ferland, Russell J. ;

Greenberg, Michael E. ;

Walsh, Christopher A. .

SCIENCE, 2008, 321 (5886) :218-223

[10] A Genome-Wide Investigation of SNPs and CNVs in Schizophrenia [J].

Need, Anna C. ;

Ge, Dongliang ;

Weale, Michael E. ;

Maia, Jessica ;

Feng, Sheng ;

Heinzen, Erin L. ;

Shianna, Kevin V. ;

Yoon, Woohyun ;

Kasperaviciute, Dalia ;

Gennarelli, Massimo ;

Strittmatter, Warren J. ;

Bonvicini, Cristian ;

Rossi, Giuseppe ;

Jayathilake, Karu ;

Cola, Philip A. ;

McEvoy, Joseph P. ;

Keefe, Richard S. E. ;

Fisher, Elizabeth M. C. ;

St. Jean, Pamela L. ;

Giegling, Ina ;

Hartmann, Annette M. ;

Moeller, Hans-Juergen ;

Ruppert, Andreas ;

Fraser, Gillian ;

Crombie, Caroline ;

Middleton, Lefkos T. ;

St. Clair, David ;

Roses, Allen D. ;

Muglia, Pierandrea ;

Francks, Clyde ;

Rujescu, Dan ;

Meltzer, Herbert Y. ;

Goldstein, David B. .

PLOS GENETICS, 2009, 5 (02)

← 1 2 3 →