Adalimumab in ulcerative colitis: Two cases of mucosal healing and clinical response at two years

被引：30

作者：

Barreiro-de Acosta, Manuel ^{[1
]}

Lorenzo, Aurelio ^{[1
]}

Enrique Dominguez-Munoz, Juan ^{[1
]}

机构：

[1] Univ Hosp Santiago de Compostela, Dept Gastroenterol, E-15706 Santiago De Compostela, Spain

来源：

WORLD JOURNAL OF GASTROENTEROLOGY | 2009年 / 15卷 / 30期

关键词：

Adalimumab; Ulcerative colitis; Mucosal healing; Maintenance treatment; INFLAMMATORY-BOWEL-DISEASE; LOST RESPONSE; THERAPY; INFLIXIMAB; INTOLERANCE; INDUCTION;

D O I：

10.3748/wjg.15.3814

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

Infliximab (IFX) is currently the only biologic therapy used in the treatment of moderate-to-severe ulcerative colitis (UC). In the years to come, more biologic therapies will have a role in the management of mode rate-to-severe UC. We report on two patients with steroid-dependent UC who, due to adverse reactions to IFX, have been under therapy with adalimumab for two years. Both patients received concomitant immunosuppressive treatment. Long term clinical remission and mucosal healing are described. (C) 2009 The WJG Press and Baishideng. All rights reserved.

引用

页码：3814 / 3816

页数：3

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