Parenteral administration of medium- but not long-chain lipid emulsions may increase the risk for infections by Candida albicans

被引：23

作者：

Wanten, GJ

Netea, MG

Naber, TH

Curfs, JH

Jacobs, LE

Verver-Jansen, TJ

Kullberg, BJ

机构：

[1] Univ Med Ctr Nijmegen, Dept Gastroenterol & Hepatol, NL-6525 GA Nijmegen, Netherlands

[2] Univ Med Ctr Nijmegen, Dept Internal Med, NL-6525 GA Nijmegen, Netherlands

[3] Univ Med Ctr Nijmegen, Dept Med Microbiol, NL-6525 GA Nijmegen, Netherlands

来源：

INFECTION AND IMMUNITY | 2002年 / 70卷 / 11期

关键词：

D O I：

10.1128/IAI.70.11.6471-6474.2002

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Intravenous administration to volunteers of an emulsion of medium-chain lipids, but not of an emulsion of pure long-chain lipids or a placebo, increased the growth of Candida albicans in serum and modulated Candida-induced cytokine production by mononuclear cells in a way suggesting that medium-chain, but not long-chain, triglycerides increase the risk for infections by Candida.

引用

收藏

页码：6471 / 6474

页数：4

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