Dry eye in 2008

被引:33
作者
Abelson, Mark B. [1 ,2 ]
Ousler, George W., III [1 ]
Maffei, Ciera [1 ]
机构
[1] Ora, Andover, MA 01810 USA
[2] Harvard Univ, Sch Med, Schepens Eye Res Inst, Boston, MA USA
关键词
dry eye; keratoconjunctivitis sicca; tear film; tears; FATTY-ACIDS; TEAR FILM; PREVALENCE; DISEASE; LASIK;
D O I
10.1097/ICU.0b013e32832b7578
中图分类号
R77 [眼科学];
学科分类号
100212 [眼科学];
摘要
Purpose of review Although researchers continue to investigate the multifarious etiologic, anatomical, physiological, and pathological factors of dry eye, successful treatment remains a challenge. Recent findings Dry eye prevalence is substantial across populations and the term 'dry eye' is used to describe numerous causes and varied pathophysiologies. Advanced study of the physiological aspects of the ocular anatomy (e.g. cornea and conjunctiva, tear film, eyelids) allows improved understanding of the mechanisms involved in dry eye and the impact of different causes on these entities. Sophisticated diagnostics are being developed to efficiently identify dry eye. Management options include a variety of novel agents in the pipeline. Summary The development of improved etiological understanding and diagnostics for dry eye, as well as emerging therapeutics, will likely allow targeted therapy in the future.
引用
收藏
页码:282 / 286
页数:5
相关论文
共 33 条
[1]
ABELSON MB, 2008, ALBERT JAKOBIECS PRI, P281
[2]
Effect of Thin Femtosecond LASIK Flaps on Corneal Sensitivity and Tear Function [J].
Barequet, Irina S. ;
Hirsh, Ami ;
Levinger, Samuel .
JOURNAL OF REFRACTIVE SURGERY, 2008, 24 (09) :897-902
[3]
Dry eye disease: The scale of the problem [J].
Brewitt, H ;
Sistani, F .
SURVEY OF OPHTHALMOLOGY, 2001, 45 :S199-S202
[4]
On the lipid composition of human meibum and tears: Comparative analysis of nonpolar lipids [J].
Butovich, Igor A. .
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2008, 49 (09) :3779-3789
[5]
Tear lipocalin and lysozyme in Sjogren and non-Sjogren dry eye [J].
Caffery, Barbary ;
Joyce, Elizabeth ;
Boone, Adrienne ;
Slomovic, Allan ;
Simpson, Trefford ;
Jones, Lyndon ;
Senchyna, Michelle .
OPTOMETRY AND VISION SCIENCE, 2008, 85 (08) :661-667
[6]
Casavant J, 2005, INVEST OPHTH VIS SCI, V46
[7]
Contact Lens Wear Affects Tear Film Evaporation [J].
Guillon, Michel ;
Maissa, Cecile .
EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE, 2008, 34 (06) :326-330
[8]
Differences in meibomian fatty acid composition in patients with meibomian gland dysfunction and aqueous-deficient dry eye [J].
Joffre, C. ;
Souchier, M. ;
Gregoire, S. ;
Viau, S. ;
Bretillon, L. ;
Acar, N. ;
Bron, A. M. ;
Creuzot-Garcher, C. .
BRITISH JOURNAL OF OPHTHALMOLOGY, 2008, 92 (01) :116-119
[9]
Five-year outcome of LASIK for myopia [J].
Kato, Naoko ;
Toda, Ikuko ;
Hori-Komai, Yoshiko ;
Sakai, Chikako ;
Tsubota, Kazuo .
OPHTHALMOLOGY, 2008, 115 (05) :839-844
[10]
Kokke Karolien H, 2008, Cont Lens Anterior Eye, V31, P141, DOI 10.1016/j.clae.2007.12.001