The development of efficient protocols for the palladium-catalyzed cyclization reactions of secondary amides and carbamates

被引:213
作者
Yang, BH [1 ]
Buchwald, SL [1 ]
机构
[1] MIT, Dept Chem, Cambridge, MA 02139 USA
关键词
D O I
10.1021/ol9905351
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
With the proper choice of palladium catalyst, ligand, and base, five, six, and seven-membered rings are formed efficiently from secondary amide or secondary carbamate precursors, offering significant improvements to currently existing methodology.
引用
收藏
页码:35 / 37
页数:3
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