Immune therapy with macrophages: Present status and critical requirements for implementation

被引：6

作者：

Bartoleyns, J ^{[1
]}

RometLemonne, JL ^{[1
]}

Chokri, M ^{[1
]}

Lopez, M ^{[1
]}

机构：

[1] INSERM,PARIS,FRANCE

来源：

IMMUNOBIOLOGY | 1996年 / 195卷 / 4-5期

关键词：

D O I：

10.1016/S0171-2985(96)80021-0

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Adoptive transfer of activated macrophages has been validated in animal experimental tumor models: clinical trials are ongoing (70 patients up to now). The mechanisms involved are reviewed as well as improved and standardized procedures for macrophage differentiation and activation. New developments including specific Ag presentation and gene therapy are discussed.

引用

页码：550 / 562

页数：13

共 49 条

[1]

ADAMS DO, 1988, MACROPHAGES CANCER, P27

[2]

ANDERSON C, 1992, NATURE, V360, P399

[3]

ANDREESEN R, 1990, CANCER RES, V50, P7450

[4] SURFACE PHENOTYPE ANALYSIS OF HUMAN MONOCYTE TO MACROPHAGE MATURATION [J].

ANDREESEN, R ;

BRUGGER, W ;

SCHEIBENBOGEN, C ;

KREUTZ, M ;

LESER, HG ;

REHM, A ;

LOHR, GW .

JOURNAL OF LEUKOCYTE BIOLOGY, 1990, 47 (06) :490-497

[5] ACTIVATED MACROPHAGES INDUCE STRUCTURAL ABNORMALITIES OF THE T-CELL RECEPTOR-CD3 COMPLEX [J].

AOE, T ;

OKAMOTO, Y ;

SAITO, T .

JOURNAL OF EXPERIMENTAL MEDICINE, 1995, 181 (05) :1881-1886

[6]

Arceci R J, 1995, Curr Opin Hematol, V2, P268

[7] CLINICAL-SYSTEMS FOR THE PRODUCTION OF HUMAN-CELLS AND TISSUES [J].

ARMSTRONG, RD ;

OGIER, WC ;

MALUTA, J .

BIO-TECHNOLOGY, 1995, 13 (05) :449-&

[8]

AUDRAN R, 1994, CANCER IMMUNOL IMMUN, V39, P299, DOI 10.1007/s002620050129

[9]

BARTHOLEYNS J, 1988, CANCER DETECT PREV, V12, P413

[10]

BARTHOLEYNS J, 1991, ANTICANCER RES, V11, P1201

← 1 2 3 4 5 →