Requirement for homologous recombination functions for expression of the mutA mistranslator tRNA-induced mutator phenotype in Escherichia coli

被引:11
作者
Ren, L [1 ]
Al Mamun, AM [1 ]
Humayun, MZ [1 ]
机构
[1] Univ Med & Dent New Jersey, New Jersey Med Sch, Dept Microbiol & Mol Genet, Newark, NJ 07103 USA
关键词
D O I
10.1128/JB.182.5.1427-1431.2000
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Expression of the Escherichia coli mutA mutator phenotype requires recA, recB, recC, ruvA, and ruvC gene, but not recD, recF, recO, or recR genes. Thus, the recBCD-dependent homologous recombination system is a component of the signal pathway that activates an error-prone DNA polymerase in mutA cells.
引用
收藏
页码:1427 / 1431
页数:5
相关论文
共 30 条
[1]   Escherichia coli cells bearing mutA, a mutant glyV tRNA gene, express a recA-dependent error-prone DNA replication activity [J].
Al Mamun, AAM ;
Rahman, MS ;
Humayun, MZ .
MOLECULAR MICROBIOLOGY, 1999, 33 (04) :732-740
[2]   THE LEXA GENE-PRODUCT REPRESSES ITS OWN PROMOTER [J].
BRENT, R ;
PTASHNE, M .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (04) :1932-1936
[3]  
Cairns J, 1998, GENETICS, V148, P1433
[4]  
DEWITT SK, 1962, GENETICS, V47, P577
[5]  
Foster PL, 1999, GENETICS, V152, P15
[6]  
Foster PL, 1998, GENETICS, V148, P1453
[7]   SOS and Mayday:: multiple inducible mutagenic pathways in Escherichia coli [J].
Humayun, MZ .
MOLECULAR MICROBIOLOGY, 1998, 30 (05) :905-910
[8]  
JACOBSEN JS, 1989, GENETICS, V121, P213
[9]   Stable DNA replication: Interplay between DNA replication, homologous recombination, and transcription [J].
Kogoma, T .
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, 1997, 61 (02) :212-+
[10]   BIOCHEMISTRY OF HOMOLOGOUS RECOMBINATION IN ESCHERICHIA-COLI [J].
KOWALCZYKOWSKI, SC ;
DIXON, DA ;
EGGLESTON, AK ;
LAUDER, SD ;
REHRAUER, WM .
MICROBIOLOGICAL REVIEWS, 1994, 58 (03) :401-465