Commentary: Genes as instruments for evaluation of markers and causes

被引:8
作者
Glynn, Robert J. [1 ]
机构
[1] Brigham & Womens Hosp, Div Prevent Med, Boston, MA 02215 USA
关键词
D O I
10.1093/ije/dyl107
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
引用
收藏
页码:932 / 934
页数:3
相关论文
共 13 条
[1]   Insight into the nature of the CRP-coronary event association using Mendelian randomization [J].
Casas, Juan P. ;
Shah, Tina ;
Cooper, Jackie ;
Hawe, Emma ;
McMahon, Alex D. ;
Gaffney, Dairena ;
Packard, Christopher J. ;
O'Reilly, Denis S. ;
Juhan-Vague, Irene ;
Yudkin, John S. ;
Tremoli, Elena ;
Margaglione, Maurizio ;
Di Minno, Giovanni ;
Hamsten, Anders ;
Kooistra, Teake ;
Stephens, Jeffrey W. ;
Hurel, Steven J. ;
Livingstone, Shona ;
Colhoun, Helen M. ;
Miller, George J. ;
Bautista, Leonelo E. ;
Meade, Tom ;
Sattar, Naveed ;
Humphries, Steve E. ;
Hingorani, Aroon D. .
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2006, 35 (04) :922-931
[2]   Epidemiological methods for studying genes and environmental factors in complex diseases [J].
Clayton, D ;
McKeigue, PM .
LANCET, 2001, 358 (9290) :1356-1360
[3]   An introduction to instrumental variables for epidemiologists [J].
Greenland, S .
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2000, 29 (04) :722-729
[4]   Contribution of clinical correlates and 13 C-reactive protein gene polymorphisms to interindividual variability in serum C-reactive protein level [J].
Kathiresan, S ;
Larson, MG ;
Vasan, RS ;
Guo, CY ;
Gona, P ;
Keaney, JF ;
Wilson, PWF ;
Newton-Cheh, C ;
Musone, SL ;
Camargo, AL ;
Drake, JA ;
Levy, D ;
O'Donnell, CJ ;
Hirschhorn, JN ;
Benjamin, EJ .
CIRCULATION, 2006, 113 (11) :1415-1423
[5]   Association of common CRP gene variants with CRP levels and cardiovascular events [J].
Miller, DT ;
Zee, RYL ;
Danik, JS ;
Kozlowski, P ;
Chasman, DI ;
Lazarus, R ;
Cook, NR ;
Ridker, PM ;
Kwiatkowski, DJ .
ANNALS OF HUMAN GENETICS, 2005, 69 :623-638
[6]   Limits to causal inference based on mendelian randomization: A comparison with randomized controlled trials [J].
Nitsch, D ;
Molokhia, M ;
Smeeth, L ;
DeStavola, BL ;
Whittaker, JC ;
Leon, DA .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 2006, 163 (05) :397-403
[7]   Rosuvastatin in the primary prevention of cardiovascular disease among patients with low levels of low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein - Rationale and design of the JUPITER trial [J].
Ridker, PM .
CIRCULATION, 2003, 108 (19) :2292-2297
[8]   C-reactive protein levels and outcomes after statin therapy [J].
Ridker, PM ;
Cannon, CP ;
Morrow, D ;
Rifai, N ;
Rose, LM ;
McCabe, CH ;
Pfeffer, MA ;
Braunwald, E .
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 352 (01) :20-28
[9]   Causation and causal inference in epidemiology [J].
Rothman, KJ ;
Greenland, S .
AMERICAN JOURNAL OF PUBLIC HEALTH, 2005, 95 :S144-S150
[10]   'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease? [J].
Smith, GD ;
Ebrahim, S .
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2003, 32 (01) :1-22