Assessment of proliferating cell nuclear antigen in nasopharyngeal carcinoma tissue and its relation to clinical findings

被引：7

作者：

Chan, ATC

Ho, S

Teo, PML

Tjong, J

Choi, J

Lee, WY

Chang, AR

Kwan, WH

Leung, WT

Johnson, PJ

机构：

[1] PRINCE WALES HOSP, SIR YK PAO CANC CTR, SHATIN, HONG KONG

[2] PRINCE WALES HOSP, DEPT ANAT & CELLULAR PATHOL, SHATIN, HONG KONG

来源：

ORAL ONCOLOGY | 1997年 / 33B卷 / 01期

关键词：

nasopharyngeal carcinoma; proliferating cell nuclear antigen; labelling index;

D O I：

10.1016/S0964-1955(96)00029-2

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

47 newly diagnosed patients with nasopharyngeal carcinoma (NPC) were studied using the proliferating cell nuclear antigen (PCNA) immunostaining technique. The results were reproducible as shown by assessment of three separate sections performed for each patient. No statistical correlation was found between PCNA labelling index (LI) and Ho's clinical staging or time required to achieve complete remission of the local disease. A higher PCNA LI was associated with a poorer disease-free survival. The literature on the use of PCNA in human tumours is reviewed. (C) 1997 Elsevier Science Ltd. All rights reserved.

引用

页码：13 / 18

页数：6

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