Antibiotic selection in obstetric patients

Penicillin and ampicillin are of primary value in treating infections caused by aerobic gram-positive organisms such as group B streptococci and enterococci. The extended spectrum cephalosporins and penicillins provide excellent coverage against the broad range of pelvic pathogens. Clindamycin and metronidazole target anaerobic organisms, whereas aminoglycosides and aztreonam are specific for aerobic gram-negative bacilli. Erythromycin and azithromycin are useful for treating obstetric patients with infections caused by mycoplasmas and Chlamydia trachomatis.