Complementary metal oxide semiconductor cantilever arrays on a single chip: Mass-sensitive detection of volatile organic compounds

被引:211
作者
Lange, D [1 ]
Hagleitner, C [1 ]
Hierlemann, A [1 ]
Brand, O [1 ]
Baltes, H [1 ]
机构
[1] Swiss Fed Inst Technol, Phys Elect Lab, CH-8093 Zurich, Switzerland
关键词
D O I
10.1021/ac011269j
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The sensing behavior of polymer-coated resonant cantilevers for mass-sensitive detection of volatile organic compounds was investigated. Industrial complementary metal oxide semiconductor (CMOS) technology combined with subsequent CMOS-compatible micromachining was used to fabricate a single-chip system comprising the transducers and all necessary driving and signal-conditioning circuitry. An analytical model was developed to describe the mass-sensing mechanism of polymer-coated resonant cantilevers. The model was validated by measurements of various gaseous analytes. As an exemplary application, the quantitative analysis of a binary mixture using an array of four cantilevers is described. Experimental results are given for the concentration prediction of a mixture of n-octane and toluene. Finally, it was established that the limit of detection achieved with cantilever sensors is comparable to that of other acoustic wave-based gas sensors.
引用
收藏
页码:3084 / 3095
页数:12
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