Nanocapsule technology: A review

被引:370
作者
Couvreur, P [1 ]
Barratt, G [1 ]
Fattal, E [1 ]
Legrand, P [1 ]
Vauthier, C [1 ]
机构
[1] Univ Paris Sud, CNRS, UMR 8612, F-92296 Chatenay Malabry, France
来源
CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS | 2002年 / 19卷 / 02期
关键词
nanocapsules; interfacial polymerization; nanodeposition; solvent evaporation; drug targeting;
D O I
10.1615/CritRevTherDrugCarrierSyst.v19.i2.10
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Nanocapsules are submicroscopic colloidal drug carrier systems composed of an oily or an aqueous core surrounded by a thin polymer membrane. Two technologies can be used to obtain such nanocapsules: the interfacial polymerization of a monomer or the interfacial nanodeposition of a preformed polymer. This article is an extended review of these nanocapsule technologies and their applications for the treatment of various diseases (including cancer and infections).
引用
收藏
页码:99 / 134
页数:36
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