If the 'adaptive' immune system can recognize a significant portion of the pathogenic universe to which the 'innate' immune system is blind, then ...

被引：9

作者：

Cohn, M ^{[1
]}

机构：

[1] Salk Inst Biol Studies, Conceptual Immunol Grp, La Jolla, CA 92037 USA

来源：

SCANDINAVIAN JOURNAL OF IMMUNOLOGY | 2004年 / 60卷 / 1-2期

关键词：

D O I：

10.1111/j.0300-9475.2004.01449.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The 'adaptive' immune repertoire functionally recognizes pathogens (and their toxic products) that the 'innate' defense system misses. This requires that the self-nonself discrimination and the regulation of effector output be dependent primarily on somatic learning mechanisms (i.e. on the somatically generated, large, random 'adaptive' immune paratopes repertoire).

引用

页码：1 / 2

页数：2

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