Catalytic performance of a supramolecular bienzyme complex formed with artificial aminotransferase and natural lactate dehydrogenase

被引：18

作者：

Kikuchi, J

Kamijyo, Y

Etoh, H

Murakami, Y

机构：

[1] Inst. Fundamental Res. Organ. Chem., Kyushu University, Fukuoka 812-81, Hakozaki, Higashi-ku

来源：

CHEMISTRY LETTERS | 1996年 / 06期

关键词：

D O I：

10.1246/cl.1996.427

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A supramolecular bienzyme complex was constituted in a combination of a catalytic bilayer membrane as an artificial aminotransferase with a natural lactate dehydrogenase and the resulting cooperative system enhanced the catalytic activity of the artificial enzyme to promote a sequential transformation of alpha-amino acids to the corresponding alpha-hydroxy acids via formation of alpha-keto acids, exhibiting a marked substrate specificity.

引用

页码：427 / 428

页数：2

共 7 条

[1]

Holbrook J.J ., 1975, ENZYMES, VXI, P191

[2] ENANTIOSELECTIVE CATALYSIS BY A SUPRAMOLECULAR BILAYER-MEMBRANE AS AN ARTIFICIAL AMINOTRANSFERASE - STEREOCHEMICAL ROLES OF AN L-LYSINE RESIDUE AND L-PHENYLALANINE AT THE REACTION SITE [J].