Are transposable elements simply silenced or are they under house arrest?

被引:15
作者
Biemont, Christian [1 ]
机构
[1] Univ Lyon 1, Lab Biometrie & Biol Evolut, CNRS, UMR 5558, F-69622 Villeurbanne, France
关键词
RNA INTERFERENCE; DNA; RETROTRANSPOSONS; HETEROCHROMATIN; EVOLUTION;
D O I
10.1016/j.tig.2009.05.006
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Despite their role as key players in evolution, it is commonly thought that transposable elements are selected against and silenced. However, their importance in chromosomal biology and, therefore, cell division suggests that their presence in many eukaryote genomes is the result of their having been selected as major components of heterochromatin.
引用
收藏
页码:333 / 334
页数:2
相关论文
共 16 条
[1]   Genetics -: Junk DNA as an evolutionary force [J].
Biemont, Christian ;
Vieira, Cristina .
NATURE, 2006, 443 (7111) :521-524
[2]   Drosophila PIWI associates with chromatin and interacts directly with HP1a [J].
Brower-Toland, Brent ;
Findley, Seth D. ;
Jiang, Ling ;
Liu, Li ;
Yin, Hang ;
Dus, Monica ;
Zhou, Pei ;
Elgin, Sarah C. R. ;
Lin, Haifan .
GENES & DEVELOPMENT, 2007, 21 (18) :2300-2311
[3]   LINE Retrotransposon RNA Is an Essential Structural and Functional Epigenetic Component of a Core Neocentromeric Chromatin [J].
Chueh, Anderly C. ;
Northrop, Emma L. ;
Brettingham-Moore, Kate H. ;
Choo, K. H. Andy ;
Wong, Lee H. .
PLOS GENETICS, 2009, 5 (01)
[4]   Revising the selfish DNA hypothesis - new evidence on accumulation of transposable elements in heterochromatin [J].
Dimitri, P ;
Junakovic, N .
TRENDS IN GENETICS, 1999, 15 (04) :123-124
[5]   Chromodomains direct integration of retrotransposons to heterochromatin [J].
Gao, Xiang ;
Hou, Yi ;
Ebina, Hirotaka ;
Levin, Henry L. ;
Voytas, Daniel F. .
GENOME RESEARCH, 2008, 18 (03) :359-369
[6]   Centromere sequence and dynamics in Dictyostelium discoideum [J].
Gloeckner, Gernot ;
Heidel, Andrew J. .
NUCLEIC ACIDS RESEARCH, 2009, 37 (06) :1809-1816
[7]   The role of RNA interference in heterochromatic silencing [J].
Lippman, Z ;
Martienssen, R .
NATURE, 2004, 431 (7006) :364-370
[8]   Conflict begets complexity: the evolution of centromeres [J].
Malik, HS ;
Henikoff, S .
CURRENT OPINION IN GENETICS & DEVELOPMENT, 2002, 12 (06) :711-718
[9]   Maintenance of heterochromatin by RNA interference of tandem repeats [J].
Martienssen, RA .
NATURE GENETICS, 2003, 35 (03) :213-214
[10]   Host defenses to transposable elements and the evolution of genomic imprinting [J].
McDonald, JF ;
Matzke, MA ;
Matzke, AJ .
CYTOGENETIC AND GENOME RESEARCH, 2005, 110 (1-4) :242-249