The Protein Data Bank: Current status and future challenges

被引:21
作者
Abola, EE
Manning, NO
Prilusky, J
Stampf, DR
Sussman, JL
机构
[1] WEIZMANN INST SCI, BIOINFORMAT UNIT, IL-76100 REHOVOT, ISRAEL
[2] WEIZMANN INST SCI, DEPT BIOL STRUCT, IL-76100 REHOVOT, ISRAEL
[3] BROOKHAVEN NATL LAB, DEPT BIOL, UPTON, NY 11973 USA
关键词
database; federation; NMR; protein structure; three-dimensional structure; x-ray crystallography;
D O I
10.6028/jres.101.025
中图分类号
TH7 [仪器、仪表];
学科分类号
0804 ; 080401 ; 081102 ;
摘要
Protein Data Bank (PDB) is an archive of experimentally determined three-dimensional structures of proteins, nucleic acids, and other biological macromolecules with a 25 year history of service to a global community. PDB is being replaced by 3DB, the Three-Dimensional Database of Biomolecular Structures that will continue to operate from Brookhaven National Laboratory. 3DB will be a highly sophisticated knowledge-based system for archiving and accessing structural information that combines the advantages of object oriented and relational database systems. 3DB will operate as a direct-deposition archive that will also accept third-party supplied annotations. Conversion of PDB to 3DB will be evolutionary, providing a high degree of compatibility with existing software.
引用
收藏
页码:231 / 241
页数:11
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