Epidemiologic Trends in Head and Neck Cancer and Aids in Diagnosis

被引:659
作者
Vigneswaran, Nadarajah [1 ]
Williams, Michelle D. [2 ]
机构
[1] Univ Texas Houston, Sch Dent Houston, Oral & Maxillofacial Pathol Biopsy Serv, Houston, TX 77054 USA
[2] Univ Texas MD Anderson Canc Ctr, Dept Pathol, Head & Neck Sect, Surg Pathol Fellowship Program, Houston, TX 77030 USA
关键词
Epidemiologic trends; Head and neck cancer; Diagnosis; Squamous cell carcinomas; SQUAMOUS-CELL CARCINOMA; ORAL EPITHELIAL DYSPLASIA; HUMAN-PAPILLOMAVIRUS; TREATMENT FAILURE; FANCONI-ANEMIA; TONGUE; LESIONS; PROGRESSION; MANAGEMENT; TOBACCO;
D O I
10.1016/j.coms.2014.01.001
中图分类号
R78 [口腔科学];
学科分类号
100302 [口腔临床医学];
摘要
Head and neck squamous cell carcinoma is the sixth most common cancer worldwide predominately associated with tobacco use. Changing cause and increased incidence in oropharyngeal carcinomas is associated with high-risk types of human papilloma virus and has an improved survival. Optical devices may augment visual oral examination; however, their lack of specificity still warrants tissue evaluation/biopsy. Histologic factors of oral carcinomas are critical for patient management and prognostic determination. Clinical biomarkers are still needed to improve early detection, predict malignant transformation, and optimize therapies.
引用
收藏
页码:123 / +
页数:20
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