A general asymmetric access to the podocarpane diterpenoids

被引：6

作者：

Fujiwara, Y ^{[1
]}

Yamato, T ^{[1
]}

Bando, T ^{[1
]}

Shishido, K ^{[1
]}

机构：

[1] UNIV TOKUSHIMA,INST MED RESOURCES,TOKUSHIMA 770,JAPAN

来源：

TETRAHEDRON-ASYMMETRY | 1997年 / 8卷 / 16期

关键词：

D O I：

10.1016/S0957-4166(97)00347-9

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

An efficient and enantiocontrolled total synthesis of (+)-O-methylpodocarpic acid 2 has been accomplished by employing a combined strategy of the lipase-mediated kinetic resolution of the tricyclic allyl alcohol (+/-)-7 and a highly diastereoselective silylmethyl radical cyclization of 5 leading to the tetracyclic silyl ether 4. (C) 1997 Published by Elsevier Science Ltd.

引用

页码：2793 / 2799

页数：7

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