Sarcoglane, a new cytotoxic diterpene from Sarcophyton glaucum

被引：21

作者：

Fridkovsky, E

Rudi, A

Benayahu, Y

Kashman, Y

Schleyer, M

机构：

[1] TEL AVIV UNIV,SCH CHEM,IL-69978 TEL AVIV,ISRAEL

[2] TEL AVIV UNIV,DEPT ZOOL,IL-69978 TEL AVIV,ISRAEL

[3] OCEANOG RES INST,DURBAN,SOUTH AFRICA

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 38期

关键词：

D O I：

10.1016/0040-4039(96)01513-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Sarcoglane (1) a new tricyclo[7,5,0(10,14)]tetradecane diterpenoid has been isolated from the Indo-Pacific soft coral Sarcophyton glaucum. The structure of compound 1, which is cytotoxic to fertilized sea urchin eggs, was defined by spectral methods and mainly 1D and 2D NMR experiments. Sarcoglane possesses an unprecedented tricyclic carbon skeleton, biogenetically, closely related to the cembrane and xeniaphyllane diterpenoids. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：6909 / 6910

页数：2

共 12 条

[1]

ALBERICCI M, 1978, B SOC CHIM BELG, V87, P487

[2] SARCOPHINE, A NEW EPOXY CEMBRANOLIDE FROM MARINE ORIGIN [J].