Di- and triterpenoids from Tripterygium hypoglaucum

被引：42

作者：

Duan, HG

Kawazoe, K

Bando, M

Kido, M

Takaishi, Y

机构：

[1] UNIV TOKUSHIMA,FAC PHARMACEUT SCI,TOKUSHIMA 770,JAPAN

[2] OTSUKA PHARMACEUT CO LTD,TOKUSHIMA 77101,JAPAN

来源：

PHYTOCHEMISTRY | 1997年 / 46卷 / 03期

关键词：

Tripterygium hypoglaucum; Celastraceae; triterpene; diterpene; celastolide; triptohypol; hypodiol;

D O I：

10.1016/S0031-9422(97)00288-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The methanol extract of dried root outer bark of Tripterygium hypoglaucum (Levl.) Hutch afforded five new triterpenes: 2,3-seco-2,24-epoxy-D:A-friedoolenane-2, 24-olide-29-oic acid named celastolide, 2,23-dihydroxy-3-methoxy-6-oxo-1,3,5(10), 8-tetraene-24-nor-D:A-friedoolenane-29-oic acid, 2-hydroxy-3-methoxy-6-oxo-1,3,5(10), 8-tetraene-24-nor-D : A-friedoolenane-29-oic acid, 2,3-dihydroxy-1,3,5(10), 8-tetraene-24-nor-D: A-friedoolenane-29-oic acid and 3 beta,11 alpha-dihydroxy-13(18)-ene-oleanane named triptohypol A, B and C and hypodiol, and two new diterpenes: 3 beta,14,19-trihydroxy-abieta-8,11,13-triene and 7-oxo-11,13-dihydroxy-19(4-3)-abeo-abieta-3,8,11,13-tetraene-19,18-olide named triptobenzene J and K, and 18 known compounds. Their structures were established on the basis of chemical and spectroscopic studies. (C) 1997 Elsevier Science Ltd.

引用

页码：535 / 543

页数：9

共 39 条

[1] HIRSUDIOL, A TRITERPENOID FROM COCCULUS-HIRSUTUS [J].