Alterations in morning cortisol associated with PTSD in women with breast cancer

被引：35

作者：

Luecken, LJ ^{[1
]}

Dausch, B

Gulla, V

Hong, R

Compas, BE

机构：

[1] Arizona State Univ, Dept Psychol, Tempe, AZ 85287 USA

[2] Univ Vermont, Burlington, VT USA

[3] Vanderbilt Univ, Nashville, TN USA

来源：

JOURNAL OF PSYCHOSOMATIC RESEARCH | 2004年 / 56卷 / 01期

关键词：

breast cancer; cortisol; PTSD; MDD;

D O I：

10.1016/S0022-3999(03)00561-0

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Objective: Diagnosis and treatment of breast cancer can be a stressful experience, putting women at risk of posttraumatic stress disorder (PTSD). The current study investigated morning cortisol levels in newly diagnosed (i.e., within 6 months) breast cancer patients. Methods: Structured DSM-IV interviews determined current and past incidence of PTSD and major depressive disorder (MDD) in 71 women with Stage 0-3 breast cancer. Results: Significantly decreased plasma cortisol was found in women meeting current or lifetime criteria for PTSD or past diagnosis of MDD. Conclusions: These results reinforce the importance for both psychological and physiological outcomes of a clinical evaluation of both current and past psychiatric status in newly diagnosed cancer patients. (C) 2004 Elsevier Inc. All rights reserved.

引用

页码：13 / 15

页数：3

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